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Neocarzinostatin anti-LYZ (SNE-L146)

The Neocarzinostatin that bound lysozyme was isolated from the library using Phage display techonology. After affinity maturation, Neocarzinostatin variants were identified having affinities (KD=10 μM) for lysozyme as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
Neocarzinostatin
Origin
Enediyne-chromoprotein family
Core Structure
β-sandwich
Variable Regions
Loop grafting; binding cleft randomization (13 aa)
Target
Lysozyme
Species Reactivity
Chicken
Expression Host
E. coli
Affinity Constant
10 μM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
enediyne-chromoprotein family; Neocarzinostatin; LYZC
Entrez Gene ID
396218
UniProt ID
P00698

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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