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PE-A*02:01/Human PTK2 (SLDLASLIL) MHC Tetramer (CAT#: MHC-LC2719)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PTK2 of peptide SLDLASLIL covering 517-525 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Specific Inquiry
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/if_selected.jpg
Figure 2 IHC staining of human urinary bladder
Figure 2 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows moderate cytoplasmic and membranous positivity in urothelial cells)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_6_5_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_B_8_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_8_3.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_9_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_6_6.jpg
Figure 8 Breast
Figure 8 Breast
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Myoepithelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_B_1_4.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1842/66971_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Figure 10 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169398-PTK2/subcellular

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • PTK2
  • Antigen Species
  • Human
  • Peptide
  • SLDLASLIL
  • Range
  • 517-525
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015]
  • Alternative Names
  • PTK2; Focal adhesion kinase 1; FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK

Downloads

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See other products for "PTK2"

Recombinant Antibody

CAT Product Name Application Type
MOB-2031z Mouse Anti-PTK2 Recombinant Antibody (clone 11B8) WB, ELISA, ICC, IHC Mouse IgG1
ZG-0329J Mouse Anti-PTK2 Recombinant Antibody (ZG-0329J) WB, ELISA Mouse IgG
ZG-0330J Mouse Anti-PTK2 Recombinant Antibody (ZG-0330J) WB, ELISA Mouse IgG
ZG-0331J Mouse Anti-PTK2 Recombinant Antibody (ZG-0331J) WB, IHC, IF, ELISA Mouse IgG
ZG-0332J Mouse Anti-PTK2 Recombinant Antibody (ZG-0332J) WB, ICC Mouse IgG

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0748MZ Chicken Anti-FAK1 Polyclonal IgY ELISA, IHC, IP, WB Chicken antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2924 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (DS2924AB) ICC, WB IgG
MOR-4573 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (TH85DS) WB, IF, ICC, FC IgG
MOR-4678 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (TH192DS) WB, IF, ICC, IHC-P, FC, ELISA IgG
MOR-4679 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (TH193DS) IF, ICC, IHC-P, FC IgG
MOR-4680 Hi-Affi™ Recombinant Rabbit Anti-PTK2 Monoclonal Antibody (TH194DS) WB, IF, ICC, FC IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC2720 PE-A*02:07/Human PTK2 (SLDLASLIL) MHC Tetramer FCM
MHC-LC4514 PE-Mamu-A1*001:01/Human PTK2 (LTAAHALAV) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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