PE-A*02:01/Human cobB (MVLILPKPEKSLAKVEKE) MHC Tetramer (CAT#: MHC-LC3447)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human cobB of peptide MVLILPKPEKSLAKVEKE covering 281-298 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- cobB
- Antigen Species
- Human
- Peptide
- MVLILPKPEKSLAKVEKE
- Range
- 281-298
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
- Alternative Names
- cobB; NAD-dependent protein deacetylase
- UniProt ID
- D2B5T1
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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