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PE-B*39:01/Human DDX3X (SHVAVENAL) MHC Tetramer (CAT#: MHC-LC1877)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of DDX3X-derived peptide of SHVAVENAL covering 2-10 and B*39:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Specific Inquiry
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1648/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human salivary gland
Figure 2 IHC staining of human salivary gland
(Immunohistochemical staining of human salivary gland shows nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59585/159478_B_1_1_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59585/159478_B_8_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59585/159478_A_7_3.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59585/159478_A_7_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59585/159478_A_7_5.jpg
Figure 7 Testis
Figure 7 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Peritubular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59585/159478_A_6_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59585/159478_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000215301-DDX3X

Specifications

  • Allele
  • B*39:01
  • Class
  • Class I
  • Antigen
  • DDX3X
  • Antigen Species
  • Human
  • Peptide
  • SHVAVENAL
  • Range
  • 2-10
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • DDX3X; DEAD-box helicase 3, X-linked; DBX; DDX3; HLP2; DDX14; CAP-Rf; MRX102

Downloads

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See other products for "DDX3X"

Recombinant Antibody

CAT Product Name Application Type
MOB-3304z Mouse Anti-DDX3X Recombinant Antibody (clone 28B7) WB, IP, IF, IHC, ELISA Mouse IgG2b, κ
MOB-1365MZ Recombinant Mouse Anti-Human DDX3X Antibody (clone 3364D6b) WB Mouse antibody
ZG-0477F Mouse Anti-DDX3X Recombinant Antibody (ZG-0477F) WB, ICC Mouse IgG
VS3-WK37 Mouse Anti-DDX3X Recombinant Antibody (clone E3-B9) WB, ELISA Mouse IgG2a
VS3-XY573 Mouse Anti-DDX3X Recombinant Antibody (clone 6G8-F4-E3) WB, ICC Mouse IgG2a

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1880 PE-B*39:01/Human DDX3X (HVAVENAL) MHC Tetramer FCM
MHC-LC1878 APC-B*39:01/Human DDX3X (SHVAVENAL) MHC Tetramer FCM
MHC-LC1881 APC-B*39:01/Human DDX3X (HVAVENAL) MHC Tetramer FCM
MHC-LC1879 BV421-B*39:01/Human DDX3X (SHVAVENAL) MHC Tetramer FCM
MHC-LC1882 BV421-B*39:01/Human DDX3X (HVAVENAL) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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