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PE-Gogo-B*0101/Human COX6C (KRKKAYADF) MHC Tetramer (CAT#: MHC-LC3039)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human COX6C of peptide KRKKAYADF and Gogo-B*0101 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Specific Inquiry
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/if_selected.jpg
Normal Tissue
Figure 2 Heart muscle
Figure 2 Heart muscle
(High expression in heart muscle)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/98827_B_6_6_val_selected.jpg
Figure 3 Kidney
Figure 3 Kidney
(Bowman's capsule Staining: Low Intensity: Moderate Quantity: <25% Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/98827_A_9_5.jpg
Figure 4 Testis
Figure 4 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/98827_A_6_6.jpg
Figure 5 Skeletal muscle
Figure 5 Skeletal muscle
(Myocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/98827_B_1_6.jpg
Figure 6 Lymph node
Figure 6 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/98827_A_8_8.jpg
Figure 7 Cerebral cortex
Figure 7 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/98827_B_8_5.jpg
Figure 8 Colon
Figure 8 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/98827_A_9_3.jpg
Figure 9 Liver
Figure 9 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14295/98827_A_8_4.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Figure 10 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164919-COX6C

Specifications

  • Allele
  • Gogo-B*0101
  • Class
  • Class I
  • Antigen
  • COX6C
  • Antigen Species
  • Human
  • Peptide
  • KRKKAYADF
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.
  • Alternative Names
  • COX6C; cytochrome c oxidase subunit 6C

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "COX6C"

Recombinant Antibody

CAT Product Name Application Type
MOB-0190CT Recombinant Mouse anti-Human COX6C Monoclonal antibody (EML026) IHC-P, WB
VS3-FY406 Recombinant Rabbit Anti-COX6C Antibody (clone R06-1D9) WB, IHC-P Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0773 Hi-Affi™ Rabbit Anti-COX6C Recombinant Antibody (clone DS773AB) WB, IHC-P Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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