Products

Pegaspargase (TP-072CL)

Pegylated L-asparagine amidohydrolase from E. coli. Pegylation substantially (by a factor of 4) extends the protein half life.      

Specifications
Classify
Protein therapeutics providing a novel function or activity: Enzymatic degradation of small-molecule metabolites
Therapeutic
Peg-asparaginase
Trade Name
Oncaspar
Function
Provides exogenous asparaginase activity, removing available asparagine from serum; purified from E. coli
Examples of Clinical Use
Acute lymphocytic leukaemia, which requires exogenous asparagine for proliferation
References
Synonyms
L-asparagine amidohydrolase, Putative L-asparaginase precursor
UniProt
P37595
Genbank
U00096

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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