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TEM-1 β-lactamase anti-FTH1 (STE-L198)

The TEM-1 β-lactamase that bound ferritin was isolated from the library using Phage display techonology. After affinity maturation, TEM-1 β-lactamase variants were identified having affinities (KD=0.5 μM) for ferritin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
TEM-1 β-lactamase
Origin
TEM-1 β-lactamase
Core Structure
α-Helixes, β-sheets
Variable Regions
two loops
Target
Ferritin
Species Reactivity
Human
Expression Host
BL21 (DE3) cells
Affinity Constant
0.5 μM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
TEM-1 β-lactamase; TEM-1 β-lactamase; FHC; FTH; HFE5; PLIF; FTHL6; PIG15
Entrez Gene ID
2495
UniProt ID
P02794

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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