Thioredoxin scaffold protein anti-CDK2 (CAT#: STD-L202)
The Thioredoxin that bound CDK2 was isolated from the library using Phage display techonology. After affinity maturation, Thioredoxin variants were identified having affinities (KD=40 nM) for CDK2 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Testis
(Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_6_6.jpg
(Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_6_6.jpg
Figure 2 Colon
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_8_3.jpg
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_8_3.jpg
Figure 3 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_7_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_7_5.jpg
Figure 4 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Pachytene spermatocytes Staining: Low Intensity: Moderate Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_6_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Pachytene spermatocytes Staining: Low Intensity: Moderate Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_6_6.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_7_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_7_8.jpg
Figure 2 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_7_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13115/32765_A_7_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000123374-CDK2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000123374-CDK2
Figure 3 RNA cell line category: Cell line enhanced (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000123374-CDK2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000123374-CDK2
Specifications
- Scaffold Name
- Thioredoxin
- Origin
- Thioredoxin
- Core Structure
- α/β (108)
- Variable Regions
- 20 aa loop insert
- Target
- CDK2
- Expression Host
- E. coli
- Affinity Constant
- 40 nM
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Related Resources
p53 Signaling Pathway
Downloads
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See other products for "CDK2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1714z | Mouse Anti-CDK2 Recombinant Antibody (clone 21A9) | WB, FC, ICC, IF | Mouse IgG1 |
| MOB-0377CT | Recombinant Mouse anti-Human CDK20 Monoclonal antibody (EML1420) | IHC-P | |
| MRO-1767-CN | Rabbit Anti-CDK2 Polyclonal Antibody (MRO-1767-CN) | WB, IF, IHC, FC | Rabbit IgG |
| ZG-0611J | Rabbit Anti-CDK2 Recombinant Antibody (clone 2C4) | ELISA, WB, IHC, IP | Rabbit IgG |
| VS3-FY345 | Recombinant Rabbit Anti-CDK2 Antibody (clone R06-4C1) | WB, IHC-P, IP | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0627 | Hi-Affi™ Rabbit Anti-CDK2 Recombinant Antibody (clone DS627AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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