Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of thyroid cancer. It is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues containing one N-linked glycosylation site. The alpha subunit is nearly identical to that of human chorionic gonadotropin (hCG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). The alpha subunit is thought to be the effector region responsible for stimulation of adenylate cyclase (involved the generation of cAMP). The beta subunit (TSHB) is unique to TSH, and therefore determines its receptor specificity. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-372 | Recombinant Anti-human FSHB Antibody | ELISA, WB, IF, FuncS | IgG |
MOB-0112MZ | Recombinant Mouse Anti-FSH-b Antibody (clone NE.114) | ELISA | Mouse antibody |
HPAB-0363-YJ | Human Anti-FSHB Recombinant Antibody (clone B3) | ELISA, WB, FuncS | Human IgG |
VS3-FY565 | Recombinant Mouse Anti-FSHB Antibody (clone 2H7B1) | ELISA, IHC, FC | Mouse IgG2a |
VS3-FY566 | Recombinant Mouse Anti-FSHB Antibody (clone 5E7-6E5-5E7) | IHC-P | Mouse IgA |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-372-F(E) | Recombinant Anti-human FSHB Antibody Fab Fragment | IP, FuncS | Fab |
MHH-372-F(E) | Recombinant Human Anti-human FSHB Antibody Fab Fragment | ELISA, WB, FC, FuncS | Fab |
PFBC-135 | Mouse Anti-FSHB Recombinant Antibody (clone 46.3H6.B7); Fab Fragment | ELISA | Mouse Fab |
HPAB-0363-YJ-F(E) | Human Anti-FSHB Recombinant Antibody (clone B3); Fab Fragment | ELISA, WB, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-372-S(P) | Recombinant Anti-human FSHB Antibody scFv Fragment | WB, IHC, FuncS | scFv |
MHH-372-S(P) | Recombinant Human Anti-human FSHB Antibody scFv Fragment | WB, FC, FuncS | scFv |
PSBC-135 | Mouse Anti-FSHB Recombinant Antibody (clone 46.3H6.B7); scFv Fragment | ELISA | Mouse scFv |
HPAB-0363-YJ-S(P) | Human Anti-FSHB Recombinant Antibody (clone B3); scFv Fragment | ELISA, WB, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1355 | Hi-Affi™ Rabbit Anti-FSHB Recombinant Antibody (clone DS1355AB) | WB, IP | Rabbit IgG |
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