A*01:01/Influenza A PB1 (VSDGGPNLY) MHC Pentamer (CAT#: MHC-YF660)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed PB1-derived peptide of VSDGGPNLY sequence covering 591-599 and A*01:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Specifications
- Allele
- A*01:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- PB1
- Antigen Species
- Influenza A
- Peptide
- VSDGGPNLY
- Range
- 591-599
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments. The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching. 5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA. In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs. During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
- Alternative Names
- RNA-directed RNA polymerase catalytic subunit; Polymerase basic protein 1; PB1; RNA-directed RNA polymerase subunit P1
- Gene ID
- 3654616
- UniProt ID
- P03430
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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