A*02:01/Epstein Barr virus Latent membrane protein LMP-1 (YLLEMLWRL) MHC Pentamer (CAT#: MHC-YC119)

MHC multimers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a Pentamer of peptide/MHC complex with EBV-derived peptide of YLLEMLWRL sequence covering 125-133 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabeled or fluorescent labeled such as Biotin, R-PE, APC. And all of them are available in 50, 150 or 500 tests.


Specific Inquiry
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  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • Epstein Barr virus Latent membrane protein LMP-1
  • Antigen Species
  • EBV
  • Peptide
  • YLLEMLWRL
  • Range
  • 125-133
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • LMP1 acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. LMP1 functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins.
  • Alternative Names
  • HHV4_LMP-1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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