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A*02:01/Human BA46 (NLFETPVEA) MHC Pentamer (CAT#: MHC-YF323)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed BA46-derived peptide of NLFETPVEA sequence covering 194-202 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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  • Gene Expression
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/if_selected.jpg
Figure 2 IHC staining of human placenta
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8016_A_1_7_selected.jpg
Normal Tissue
Figure 3 IHC staining of human endometrium
Figure 3 IHC staining of human endometrium
(High expression. RNA expression: 444.7 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_B_5_3_val_selected.jpg
Figure 4 IHC staining of human duodenum
Figure 4 IHC staining of human duodenum
(Low expression. RNA expression: 21.2 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_9_2_val_selected.jpg
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Glial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8042_B_7_5.jpg
Figure 6 Colon
Figure 6 Colon
(Enterocytes - Microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_3.jpg
Figure 7 Liver
Figure 7 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_8_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining: High
Intensity: Strong
Quantity:>75%
Proximal tubules (microvilli)
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_5.jpg
Figure 9 Testis
Figure 9 Testis
(Cells in seminiferous ducts
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8016_A_4_6.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140545-MFGE8

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • BA46
  • Antigen Species
  • Human
  • Peptide
  • NLFETPVEA
  • Range
  • 194-202
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
  • Alternative Names
  • Milk Fat Globule-EGF Factor 8 Protein; Breast Epithelial Antigen BA46; Sperm Associated Antigen 10; Sperm Surface Protein HP47; Lactadherin; MFG-E8; HMFG; MFGM; SED1; O-Acetyl Disialoganglioside Synthase;

Downloads

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See other products for "MFGE8"

Fab Fragment Antibody

CAT Product Name Application Type
MOB-657-F(E) Recombinant Anti-human MFGE8 Antibody Fab Fragment IP, IF, FuncS Fab
MHH-657-F(E) Recombinant Human Anti-human MFGE8 Antibody Fab Fragment WB, ELISA, IHC, FuncS Fab
FAMAB-0225CQ-F(E) Mouse Anti-MFGE8 Recombinant Antibody (clone Mc3); Fab Fragment ELISA, IF, FuncS Mouse Fab
HPAB-2103-FY-F(E) Human Anti-MFGE8 Recombinant Antibody (clone HuHMFG1); Fab Fragment IA Humanized Fab
HPAB-2104-FY-F(E) Mouse Anti-MFGE8 Recombinant Antibody (clone HMFG1); Fab Fragment IA Mouse Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-657-S(P) Recombinant Anti-human MFGE8 Antibody scFv Fragment WB, FC, FuncS scFv
MHH-657-S(P) Recombinant Human Anti-human MFGE8 Antibody scFv Fragment WB, IP, FuncS scFv
FAMAB-0225CQ-S(P) Mouse Anti-MFGE8 Recombinant Antibody (clone Mc3); scFv Fragment ELISA, IF, FuncS Mouse scFv
FAMAB-0365JF-S(P) Mouse Anti-MFGE8 Recombinant Antibody (clone 3D10); scFv Fragment IB, WB, ELISA, FuncS Mouse scFv
HPAB-2103-FY-S(P) Human Anti-MFGE8 Recombinant Antibody (clone HuHMFG1); scFv Fragment IA Humanized scFv

Recombinant Antibody

CAT Product Name Application Type
MHH-657 Recombinant Human Anti-human MFGE8 Antibody IF, ELISA, FuncS IgG
MOB-1240MZ Recombinant Mouse Anti-Human MFGE8 Antibody (clone FEN56), Biotin-Conjugated ICC/IF, IHC-P, IP, WB Mouse antibody
FAMAB-0225CQ Mouse Anti-MFGE8 Recombinant Antibody (clone Mc3) ELISA, IF, Block, FuncS Mouse IgG1, κ
HPAB-2103-FY Human Anti-MFGE8 Recombinant Antibody (clone HuHMFG1) IA Human IgG1
VS1-YJ106 Mouse Anti-MFGE8 Recombinant Antibody (clone MFG-06) IHC, IHC-P Mouse IgG1

Humanized Antibody

CAT Product Name Application Type
TAB-0768CL Human Anti-MFGE8 Recombinant Antibody (TAB-0768CL) ELISA Humanized IgG
TAB-0769CL Human Anti-MFGE8 Recombinant Antibody (TAB-0769CL) ELISA Humanized IgG
TAB-0770CL Human Anti-MFGE8 Recombinant Antibody (TAB-0770CL) FC, IHC Humanized IgG
TAB-0771CL Human Anti-MFGE8 Recombinant Antibody (TAB-0771CL) ELISA Humanized IgG
TAB-0772CL Human Anti-MFGE8 Recombinant Antibody (TAB-0772CL) ELISA Humanized IgG

Mouse Antibody

CAT Product Name Application Type
TAB-0763CL-S(P) Mouse Anti-MFGE8 Recombinant Antibody; scFv Fragment (TAB-0763CL-S(P)) ELISA Mouse scFv
TAB-0764CL-S(P) Mouse Anti-MFGE8 Recombinant Antibody; scFv Fragment (TAB-0764CL-S(P)) ELISA Mouse scFv
TAB-0765CL-S(P) Mouse Anti-MFGE8 Recombinant Antibody; scFv Fragment (TAB-0765CL-S(P)) ELISA Mouse scFv
TAB-0766CL-S(P) Mouse Anti-MFGE8 Recombinant Antibody; scFv Fragment (TAB-0766CL-S(P)) ELISA Mouse scFv
TAB-0767CL-S(P) Mouse Anti-MFGE8 Recombinant Antibody; scFv Fragment (TAB-0767CL-S(P)) ELISA Mouse scFv

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC048 PE-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer FCM
MHC-LC049 APC-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer FCM
MHC-LC050 BV421-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer FCM

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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