A*02:01/Human BIR7 (VLEPPGARDV) MHC Pentamer (CAT#: MHC-YF334)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed BIR7-derived peptide of VLEPPGARDV sequence covering 230-239 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47850/1291_D11_1_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47850/1291_D11_1_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101197-BIRC7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101197-BIRC7
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- BIR7
- Antigen Species
- Human
- Peptide
- VLEPPGARDV
- Range
- 230-239
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
- Alternative Names
- Baculoviral IAP Repeat Containing 7; Melanoma Inhibitor Of Apoptosis Protein; Kidney Inhibitor Of Apoptosis Protein; Livin; RING-Type E3 Ubiquitin Transferase BIRC7; RING Finger Protein 50; ML-IAP; MLIAP;
- Gene ID
- 79444
- UniProt ID
- Q96CA5
Downloads
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See other products for "BIRC7"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2973z | Mouse Anti-BIRC7 Recombinant Antibody (MOB-2973z) | WB, ICC, IF | Mouse IgG1, κ |
| MOB-1253MZ | Mouse Anti-BIRC7 Recombinant Antibody (clone 99D680) | WB | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2973z-F(E) | Recombinant Anti-Human BIRC7 Antibody Fab Fragment | FC, IP, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2973z-S(P) | Recombinant Anti-Human BIRC7 Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC060 | PE-A*02:01/Human LIVIN (QLCPICRAPV) MHC Tetramer | FCM | |
| MHC-LC061 | APC-A*02:01/Human LIVIN (QLCPICRAPV) MHC Tetramer | FCM | |
| MHC-LC062 | BV421-A*02:01/Human LIVIN (QLCPICRAPV) MHC Tetramer | FCM | |
| MHC-YF335 | A*02:01/Human BIR7 (RLASFYDWPL) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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