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A*02:01/Human ERBB-4 (VLVKSPNHV) MHC Pentamer (CAT#: MHC-YF427)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed ERBB-4-derived peptide of VLVKSPNHV sequence covering 890-898 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
Figure 1 Kidney
Figure 1 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_7_5.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_B_8_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_7_3.jpg
Figure 4 Liver
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12016/35976_A_8_4.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AF22, EFO-21, HEK93, RPTEC TERT1, SCLC-21H, T-47d)
Figure 5 RNA cell line category: Cell line enhanced (AF22, EFO-21, HEK93, RPTEC TERT1, SCLC-21H, T-47d)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178568-ERBB4

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • ERBB-4
  • Antigen Species
  • Human
  • Peptide
  • VLVKSPNHV
  • Range
  • 890-898
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • Erb-B2 Receptor Tyrosine Kinase 4; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 4; Tyrosine Kinase-Type Cell Surface Receptor HER4; Human Epidermal Growth Factor Receptor 4; Proto-Oncogene-Like Protein C-ErbB-4; EC 2.7.10.1; P180erbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4;

Related Resources

  • Related Signaling Pathways

Downloads

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See other products for "ERBB4"

Recombinant Antibody

CAT Product Name Application Type
PABL-470 Mouse Anti-ERBB4 Recombinant Antibody (PABL-470) WB, IF, FuncS Mouse IgG
MOB-0689CT Recombinant Mouse anti-Human ERBB4 Monoclonal antibody (I5.83.9) FC
HPAB-0530YY Human Anti-ERBB4 Recombinant Antibody (HPAB-0530YY) ELISA Human IgG1
HPAB-0531YY Human Anti-ERBB4 Recombinant Antibody (HPAB-0531YY) ELISA Human IgG1
VS3-XY647 Mouse Anti-ERBB4 Recombinant Antibody (clone 2F7B2) ELISA, WB, IHC, FC Mouse IgG1

Fab Fragment Antibody

CAT Product Name Application Type
PFBL-467 Mouse Anti-ERBB4 Recombinant Antibody; Fab Fragment (PFBL-467) WB, IF, FuncS Mouse Fab
HPAB-0530YY-F(E) Human Anti-ERBB4 Recombinant Antibody; Fab Fragment (HPAB-0530YY-F(E)) ELISA Human Fab
HPAB-0531YY-F(E) Human Anti-ERBB4 Recombinant Antibody; Fab Fragment (HPAB-0531YY-F(E)) ELISA Human Fab
HPAB-0532YY-F(E) Human Anti-ERBB4 Recombinant Antibody; Fab Fragment (HPAB-0532YY-F(E)) ELISA Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
PSBL-467 Mouse Anti-ERBB4 Recombinant Antibody; scFv Fragment (PSBL-467) WB, IF, FuncS Mouse scFv
HPAB-0530YY-S(P) Human Anti-ERBB4 Recombinant Antibody; scFv Fragment (HPAB-0530YY-S(P)) ELISA Human scFv
HPAB-0531YY-S(P) Human Anti-ERBB4 Recombinant Antibody; scFv Fragment (HPAB-0531YY-S(P)) ELISA Human scFv
HPAB-0532YY-S(P) Human Anti-ERBB4 Recombinant Antibody; scFv Fragment (HPAB-0532YY-S(P)) ELISA Human scFv

Human Antibody

CAT Product Name Application Type
TAB-073CT Anti-Human HER4 Recombinant Antibody (HE4B-33) ELISA, Inhibition Human antibody
TAB-073CT-S(P) Anti-Human HER4 Recombinant Antibody scFv Fragment (HE4B-33) ELISA, Inhibition Human antibody
TAB-073CT-F(E) Anti-Human HER4 Recombinant Antibody Fab Fragment (HE4B-33) ELISA, Inhibition Human antibody

Mouse Antibody

CAT Product Name Application Type
TAB-074CT Mouse Anti-ERBB4 Recombinant Antibody (TAB-074CT) ELISA, Inhibion, WB Mouse IgG
TAB-074CT-S(P) Mouse Anti-ERBB4 Recombinant Antibody; scFv Fragment (TAB-074CT-S(P)) ELISA, Inhibion, WB Mouse scFv
TAB-074CT-F(E) Mouse Anti-ERBB4 Recombinant Antibody; Fab Fragment (TAB-074CT-F(E)) ELISA, Inhibion, WB Mouse Fab

Blocking Antibody

CAT Product Name Application Type
NEUT-743CQ Mouse Anti-ERBB4 Recombinant Antibody (clone CBL391) Block Mouse IgG2b

Neutralizing Antibody

CAT Product Name Application Type
NEUT-744CQ Mouse Anti-ERBB4 Recombinant Antibody (clone CBL930) IP, Neut, FC Mouse IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1180 Hi-Affi™ Rabbit Anti-ERBB4 Recombinant Antibody (clone DS1180AB) WB Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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