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A*02:01/Human MCL-1 (AVLPLLELV) MHC Pentamer (CAT#: MHC-YF547)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed MCL-1-derived peptide of AVLPLLELV sequence covering 139-147 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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  • Datasheet
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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/if_selected.jpg
Normal Tissue
Figure 2 Appendix
Figure 2 Appendix
(High expression in appendix)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/22739_A_1_2_val_selected.jpg
Figure 3 IHC staining of human stomach
Figure 3 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_3_1_selected.jpg
Figure 4 IHC staining of human placenta
Figure 4 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68195/ihc_selected.jpg
Figure 5 Colon
Figure 5 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_7_3.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_6_6.jpg
Figure 7 Thyroid gland
Figure 7 Thyroid gland
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_B_3_5.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enriched (U-698)
Figure 8 RNA cell line category: Cell line enriched (U-698)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143384-MCL1

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • MCL-1
  • Antigen Species
  • Human
  • Peptide
  • AVLPLLELV
  • Range
  • 139-147
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
  • Alternative Names
  • MCL1, BCL2 Family Apoptosis Regulator; Myeloid Cell Leukemia Sequence 1 (BCL2-Related); Bcl-2-Related Protein EAT/Mcl1; Myeloid Cell Leukemia 1; Bcl-2-Like Protein 3; Bcl2-L-3; Mcl1/EAT; BCL2L3; Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1;

Downloads

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Recombinant Antibody

CAT Product Name Application Type
MOB-2309z Mouse Anti-MCL1 Recombinant Antibody (clone 26F6) WB, ELISA, IF, IHC Mouse IgG1
MOB-1225CT Recombinant Mouse anti-Human MCL1 Monoclonal antibody (49H4) IHC-P
MRO-2028-CN Rabbit Anti-MCL1 Polyclonal Antibody (MRO-2028-CN) IF, IHC Rabbit IgG
PABS-0143 Human Anti-MCL1 Recombinant Antibody (Clone 01JF43) ELISA, FuncS Human IgG
VS3-WK894 Rabbit Anti-MCL1 Recombinant Antibody (VS3-WK894) WB, ICC, IF, IHC, IP, FC Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2189 Hi-Affi™ Recombinant Rabbit Anti-MCL1 Monoclonal Antibody (DS2189AB) ICC/IF, WB, IHC-P, ICC, FC, IP IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-CN1025 PE-A*03:01/Human MCL1 (RLLFFAPTR) MHC Tetramer FCM, IHC
MHC-CN1026 APC-A*03:01/Human MCL1 (RLLFFAPTR) MHC Tetramer FCM, IHC
MHC-CN1027 FITC-A*03:01/Human MCL1 (RLLFFAPTR) MHC Tetramer FCM, IHC
MHC-CN1028 A*03:01/Human MCL1 (RLLFFAPTR) MHC Tetramer FCM, IHC
MHC-YF546 A*01:01/Human MCL-1 (QSLEIISRY) MHC Pentamer FCM

Fab Fragment Antibody

CAT Product Name Application Type
PFBS-0143 Human Anti-MCL1 Recombinant Antibody (Clone 01JF43); Fab Fragment ELISA, FuncS Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
PSBS-0143 Human Anti-MCL1 Recombinant Antibody (Clone 01JF43); scFv Fragment ELISA, FuncS Human scFv

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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