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APC-A*03:01/Human BCL2L1 (RIAAWMATY) MHC Tetramer (CAT#: MHC-CN0430)


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72801/1349_F9_5_selected.jpg
Normal Tissue
Figure 2 IHC staining of human urinary bladder
Figure 2 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35734/ihc_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35734/143255_B_8_5.jpg
Figure 4 Liver
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35734/143255_A_9_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35734/143255_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35734/143255_A_6_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35734/143255_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171552-BCL2L1

Specifications

  • Allele
  • A*03:01
  • Class
  • Class I
  • Antigen
  • BCL2L1
  • Antigen Species
  • Human
  • Peptide
  • RIAAWMATY
  • Conjugate
  • APC
  • Application
  • FCM, IHC

Target

  • Antigen Introduction
  • The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
  • Alternative Names
  • BCL2 Like 1; Protein Phosphatase 1, Regulatory Subunit 52; Apoptosis Regulator Bcl-X; BCL2L; BCLX; Bcl-2-Like Protein 1;

Related Resources

  • Related Diseases

Downloads

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Chicken IgY Antibody

CAT Product Name Application Type
BRD-0068MZ Chicken Anti-BCL2L1 Polyclonal IgY WB Chicken antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
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MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-CN0425 PE-A*02:01/Human BCL2L1 (YLNDHLEPWI) MHC Tetramer FCM, IHC
MHC-CN0426 APC-A*02:01/Human BCL2L1 (YLNDHLEPWI) MHC Tetramer FCM, IHC
MHC-CN0427 FITC-A*02:01/Human BCL2L1 (YLNDHLEPWI) MHC Tetramer FCM, IHC
MHC-CN0428 A*02:01/Human BCL2L1 (YLNDHLEPWI) MHC Tetramer FCM, IHC
MHC-CN0429 PE-A*03:01/Human BCL2L1 (RIAAWMATY) MHC Tetramer FCM, IHC

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