PE-A*24:02/Human BCL2A1 (DYLQYVLQI) MHC Tetramer (CAT#: MHC-CN0421)


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
RNA Expression

Specifications

  • Allele
  • A*24:02
  • Class
  • Class I
  • Antigen
  • BCL2A1
  • Antigen Species
  • Human
  • Peptide
  • DYLQYVLQI
  • Conjugate
  • PE
  • Application
  • FCM, IHC

Target

  • Antigen Introduction
  • This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • BCL2 Related Protein A1; Hemopoietic-Specific Early Response Protein; Bcl-2-Like Protein 5; Protein BFL-1; Bcl2-L-5; BCL2L5; HBPA1; BFL1; GRS;

Related Resources

  • Related Signaling Pathways

Downloads

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Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0343 Hi-Affi™ Rabbit Anti-BCL2A1 Recombinant Antibody (clone DS343AB) WB, FC, IP, IHC, ICC Rabbit IgG

Recombinant Antibody

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