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A*24:02/Human Midkine (RYNAQCQETI) MHC Pentamer (CAT#: MHC-YF562)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Midkine-derived peptide of RYNAQCQETI sequence covering 110-119 and A*24:02 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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  • Gene Expression
  • Datasheet
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  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57126/996_H3_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human endometrium
Figure 2 IHC staining of human endometrium
(Immunohistochemical staining of human endometrium shows moderate cytoplasmic positivity in glandular cells and stroma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_B_4_3_selected.jpg
Figure 3 Colon
Figure 3 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_A_8_3.jpg
Figure 4 Testis
Figure 4 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_A_4_6.jpg
Figure 5 Endometrium
Figure 5 Endometrium
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10055/26957_B_4_3.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (NTERA-2, REH, SH-SY5Y)
Figure 6 RNA cell line category: Cell line enhanced (NTERA-2, REH, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110492-MDK

Specifications

  • Allele
  • A*24:02
  • Class
  • Class I
  • Antigen
  • Midkine
  • Antigen Species
  • Human
  • Peptide
  • RYNAQCQETI
  • Range
  • 110-119
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]
  • Alternative Names
  • Midkine; Neurite Outgrowth-Promoting Factor 2; Neurite Growth-Promoting Factor 2; Amphiregulin-Associated Protein; Midgestation And Kidney Protein; NEGF2;

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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