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  • DRB1*04:01/Human cit vimentin (GVYAT[cit]SSAV[cit]L[cit]SSVPGVR) MHC Monomer

DRB1*04:01/Human cit vimentin (GVYAT[cit]SSAV[cit]L[cit]SSVPGVR) MHC Monomer (CAT#: MHC-YF038)

This product is a MHC monomer of biotinylated peptide/MHC complex composed cit vimentin-derived peptide of GVYAT[cit]SSAV[cit]L[cit]SSVPGVR sequence covering 59-78 and DRB1*04:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line ASC TERT1
Figure 1 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1762/1774_A1_22_cr5950f6319513b_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1762/32_C3_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1762/34_C3_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Endothelial cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear
Glial cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

Neuropil
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/80/1706_B_7_5.jpg
Figure 5 Colon
Figure 5 Colon
(Endothelial cells
Staining:

High

Intensity: Strong
Quantity:>75%

Fibroblasts
Staining:

High

Intensity: Strong

Mucosal lymphoid cells
Staining:

High

Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/80/1664_B_9_3.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/80/1664_B_7_5.jpg
Figure 7 Testis
Figure 7 Testis
(Leydig cells
Staining:

High

Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Peritubular cells
Staining:

High

Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining:

High

Intensity: Strong
Quantity:>75%

Sertoli cells
Staining:

High

Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining:

High

Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/80/1664_B_6_6.jpg
Figure 8 Breast
Figure 8 Breast
(Adipocytes
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear

Myoepithelial cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/80/1706_B_2_4.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/80/1664_B_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, fHDF/TERT166)
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000026025-VIM
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, fHDF/TERT166)
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000026025-VIM

Specifications

  • Allele
  • DRB1*04:01
  • Class
  • Class II
  • Antigen
  • cit vimentin
  • Antigen Species
  • Human
  • Peptide
  • GVYAT[cit]SSAV[cit]L[cit]SSVPGVR
  • Range
  • 59-78
  • Conjugate
  • Biotin
  • Application
  • MHC Multimer

Target

  • Antigen Introduction
  • This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients.
  • Alternative Names
  • VIM; Vimentin

Downloads

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Recombinant Antibody

CAT Product Name Application Type
MOB-1153z Mouse Anti-VIM Recombinant Antibody (clone 28A3) WB, ELISA, IHC, IP Mouse IgG1, κ
MRO-1583-CN Mouse Anti-VIM Recombinant Antibody (clone A6-C1) WB, IF, IHC, FC Mouse IgG2b
MRO-2273-CN Rabbit Anti-VIM Polyclonal Antibody (MRO-2273-CN) WB, IF, IHC, FC Rabbit IgG
VS3-XY1589 Mouse Anti-VIM Recombinant Antibody (clone B4-B11) WB, ICC, IHC, FC Mouse IgG1
VS-0923-FY245 Recombinant Mouse Anti-VIM Antibody (VS-0923-FY245) ELISA, WB, IHC Mouse IgG2b

Mouse Antibody

CAT Product Name Application Type
TAB-353CQ Anti-Human VIM Recombinant Antibody (HoAKs-1) ELISA
TAB-354CQ Anti-Human VIM Recombinant Antibody (2F6-1) IF
TAB-355CQ Anti-Human VIM Recombinant Antibody (3F9-1) IF
TAB-353CQ-S(P) Anti-Human VIM Recombinant Antibody scFv Fragment (HoAKs-1) ELISA, WB
TAB-354CQ-S(P) Anti-Human VIM Recombinant Antibody scFv Fragment (2F6-1) ELISA, WB

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0741MZ Chicken Anti-VIM Polyclonal IgY ICC/IF, IHC, WB Chicken antibody

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1805 PE-DRB*01:01/Human VIM (SAVRLRSSVPGVR) MHC Tetramer FCM
MHC-LC1811 PE-DRB1*04:01/Human VIM (GVYATRSSAVRLR) MHC Tetramer FCM
MHC-LC1807 BV421-DRB*01:01/Human VIM (SAVRLRSSVPGVR) MHC Tetramer FCM
MHC-LC1813 BV421-DRB1*04:01/Human VIM (GVYATRSSAVRLR) MHC Tetramer FCM
MHC-LC3829 PE-A*02:02/Human VIM (SLTCEVDAL) MHC Tetramer FCM

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3838 Rabbit Anti-VIM Recombinant Antibody (clone DS3838AB) IHC-P Rabbit IgG

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-2717LY-F(E) Human Anti-VIM Recombinant Antibody (clone hzVSF); Fab Fragment FC, WB, Block, ELISA Humanized Fab
HPAB-0349-YJ-F(E) Mouse Anti-VIM Recombinant Antibody; Fab Fragment (HPAB-0349-YJ-F(E)) ELISA, WB, IP, ICC, IHC, FC, IF Mouse Fab
HPAB-0350-YJ-F(E) Human Anti-VIM Recombinant Antibody; Fab Fragment (HPAB-0350-YJ-F(E)) ELISA, WB, IP, ICC, IHC, FC, IF Humanized Fab

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-2717LY-S(P) Human Anti-VIM Recombinant Antibody (clone hzVSF); scfv Fragment FC, WB, Block, ELISA Humanized scfv
HPAB-0349-YJ-S(P) Mouse Anti-VIM Recombinant Antibody; scFv Fragment (HPAB-0349-YJ-S(P)) ELISA, WB, IP, ICC, IHC, FC, IF Mouse scFv
HPAB-0350-YJ-S(P) Mouse Anti-VIM Recombinant Antibody; scFv Fragment (HPAB-0350-YJ-S(P)) ELISA, WB, IP, ICC, IHC, FC, IF Mouse scFv

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