H-2Db/Influenza A virus (H1N1) Polymerase PA (TYQRTRALV) MHC Pentamer (CAT#: MHC-YC211)
MHC multimers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a Pentamer of peptide/MHC complex with IAV-derived peptide of TYQRTRALV sequence covering 147-155 and H-2Db molecule. The peptide/MHC pentamer provided here is unlabeled or fluorescent labeled such as Biotin, R-PE, APC. And all of them are available in 50, 150 or 500 tests.
Specific Inquiry
Specifications
- Allele
- H-2Db
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Influenza A virus (H1N1) Polymerase PA
- Antigen Species
- IAV
- Peptide
- TYQRTRALV
- Range
- 147-155
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- PA plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
- Alternative Names
- FLUAVs3gp1
- Gene ID
- 956535
- UniProt ID
- P03433
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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