H-2Db/Influenza A Polymerase acidic protein (SSLENFRAYV) MHC Pentamer (CAT#: MHC-YF670)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Polymerase acidic protein-derived peptide of SSLENFRAYV sequence covering 224-233 and H-2Db molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


Specific Inquiry
  • Size:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • H-2Db
  • Class
  • Class I
  • Antigen
  • Polymerase acidic protein
  • Antigen Species
  • Influenza A
  • Peptide
  • SSLENFRAYV
  • Range
  • 224-233
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
  • Alternative Names
  • Polymerase acidic protein; RNA-directed RNA polymerase subunit P2; PA

Downloads

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Chimeric Antibody

CAT Product Name Application Type
TAB-440CQ Anti-Bacillus Anthracis PA Recombinant Antibody (Obiltoxaximab) ELISA, IHC, FC, IP, IF, FuncS IgG1, κ

MHC Tetramer for Virology

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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