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Recombinant Human Anti-ATP6AP1 Soluble TCR (NC1) (KIH) (CAT#: VS-0622-YF6819)

Human TCR (NC1) recognizes ATP6AP1 peptide (KLGASPLHV) in the context of HLA-A2. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.


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Normal Tissue
Figure 1 IHC staining of human kidney
Figure 1 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in tubular and glomeruli cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15218/ihc_selected.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15218/36646_B_8_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15218/36646_A_9_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15218/36646_A_9_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15218/36646_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15218/36646_A_5_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15218/36646_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000071553-ATP6AP1

Specifications

  • Host Species
  • Human
  • Target
  • ATP6AP1
  • Species Reactivity
  • Human
  • Epitope
  • KLGASPLHV
  • MHC
  • HLA-A2
  • Clone
  • NC1
  • Type
  • Soluble TCR (KIH)
  • TCR Expression Strategy
  • KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).

Target

  • Alternative Names
  • ATPase H+ Transporting Accessory Protein 1; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump), Subunit 1; ATPase, H+ Transporting, Lysosomal Accessory Protein 1; Vacuolar Proton Pump Subunit S1; V-ATPase S1 Accessory Protein; V-ATPase Ac45 Subunit; V-ATPase Subunit S1; Protein XAP-3; ATP6IP1; ATP6S1;

Related Resources

  • Related Signaling Pathways
  • Related Diseases

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Recombinant Antibody

CAT Product Name Application Type
MOB-0487MZ Mouse Anti-ATP6AP1 Recombinant Antibody (clone CBLS-048) WB Mouse IgG1

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