Recombinant Mouse Anti-ACAN Soluble TCR (5/4E8) (KIH) (CAT#: VS-0622-YF6775)
Mouse TCR (5/4E8) recognizes ACAN peptide (ATEGRVRVNSAYQDK) in the context of H2-IAd. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38242/146198_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38242/146198_A_7_3.jpg
Figure 2 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38242/146198_A_7_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38242/146198_A_7_5.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38242/146198_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/38242/146198_B_9_5.jpg
Figure 4 RNA cell line category: Cell line enriched (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157766-ACAN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157766-ACAN
Specifications
- Host Species
- Mouse
- Target
- ACAN
- Species Reactivity
- Human
- Epitope
- ATEGRVRVNSAYQDK
- MHC
- H2-IAd
- Clone
- 5/4E8
- Type
- Soluble TCR (KIH)
- Related Disease
- Skeletal dysplasia
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- Aggrecan; Chondroitin Sulfate Proteoglycan Core Protein 1; Cartilage-Specific Proteoglycan Core Protein; Chondroitin Sulfate Proteoglycan 1; CSPG1; MSK16; AGC1; Large Aggregating Proteoglycan; Aggrecan Proteoglycan;
- Gene ID
- 176
- UniProt ID
- P16112
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3746z | Mouse Anti-ACAN Recombinant Antibody (clone 27H3) | WB, IP, IF, IHC | Mouse IgG1, κ |
| MOB-0499MZ | Mouse Anti-ACAN Recombinant Antibody (clone 7-C-5) | ELISA, IF, IHC-Fr, IHC-P, WB | Mouse IgG1 |
| MRO-0036-CN | Rabbit Anti-ACAN Recombinant Antibody (clone JA40-23) | IHC | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1814 | PE-DRB1*04:01/Human ACAN (ATEYRVRVNSAYQDK) MHC Tetramer | FCM | |
| MHC-LC1815 | APC-DRB1*04:01/Human ACAN (ATEYRVRVNSAYQDK) MHC Tetramer | FCM | |
| MHC-LC1816 | BV421-DRB1*04:01/Human ACAN (ATEYRVRVNSAYQDK) MHC Tetramer | FCM |
MHC Tetramer for Other Applications
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF037 | DRB1*04:01/Human cit aggrecan (ATEG[cit]V[cit]VNSAYQDK) MHC Monomer | MHC Multimer |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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