Recombinant Mouse Anti-IAPP Soluble TCR (BDC-5.2.9) (C-Cys) (CAT#: VS-0622-YF3730)
Mouse TCR (BDC-5.2.9) recognizes IAPP peptide (KCNTATCATQRLANFLVRSS) in the context of HLA class II. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/1947_F12_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/1947_F12_2_selected.jpg
Figure 2 High expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3_val_selected.jpg
Figure 3 Low expression in colon
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_9_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_9_3_val_selected.jpg
Figure 4 Pancreas
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3.jpg
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3.jpg
Figure 5 RNA cell line category: Cell line enhanced (U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121351-IAPP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121351-IAPP
Specifications
- Host Species
- Mouse
- Target
- IAPP
- Species Reactivity
- Mouse
- Epitope
- KCNTATCATQRLANFLVRSS
- MHC
- HLA class II
- Clone
- BDC-5.2.9
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Pancreatic cancer
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2254z | Mouse Anti-IAPP Recombinant Antibody (clone 35D9) | ICC, IF, IHC | Mouse IgG1 |
| HPAB-0295-YC | Human Anti-IAPP Recombinant Antibody (clone HlLl) | FuncS | Humanized IgG1, κ |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-375CL | Human Anti-IAPP Recombinant Antibody (TAB-375CL) | ELISA | Human IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-118CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-118CT-S(P)) | ELISA | Human scFv |
| TAB-119CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-119CT-S(P)) | ELISA | Human scFv |
| TAB-120CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-120CT-S(P)) | ELISA | Human scFv |
| TAB-118CT-F(E) | Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-118CT-F(E)) | ELISA | Human Fab |
| TAB-119CT-F(E) | Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-119CT-F(E)) | ELISA | Human Fab |
MHC Tetramer for Other Applications
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC671 | PE-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-LC672 | APC-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-LC673 | BV421-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-YF299 | A*02:01/Human IAPP (KLQVFLIVL) MHC Monomer | MHC Multimer |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-S(P) | Human Anti-IAPP Recombinant Antibody (clone HlLl); scFv Fragment | FuncS | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-F(E) | Human Anti-IAPP Recombinant Antibody (clone HlLl); Fab Fragment | FuncS | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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