PE-HLA-B*44:03/SARS-CoV-2 N (GMEVTPSGTWL) MHC Tetramer (CAT#: MHC-YF2693)
This product is a MHC tetramer of biotinylated peptide/MHC complex composed N-derived peptide of GMEVTPSGTWL sequence covering 321-331 and HLA-B*44:03 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- HLA-B*44:03
- Class
- Class I
- Antigen
- N
- Antigen Species
- SARS-CoV-2
- Peptide
- GMEVTPSGTWL
- Range
- 321-331
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
- Alternative Names
- Nucleocapsid protein, Nucleocapsid, Nucleoprotein, N, NP, Coronavirus NP, Coronavirus Nucleocapsid protein, Coronavirus Nucleocapsid, Coronavirus Nucleoprotein, Coronavirus N, SARS-CoV-2 NP, SARS-CoV-2 Nucleocapsid protein, SARS-CoV-2 Nucleocapsid, SARS-CoV-2 Nucleoprotein, SARS-CoV-2 N
- Gene ID
- 43740575
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1231CT | Recombinant Mouse anti-Other N Monoclonal antibody (iNQW 44) | ELISA, ICC/IF |
MHC Tetramer for Virology
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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