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AD1
Glycoprotein B (gB, gpUL55) is the major antigen for the induction of neutralizing antibodies against human cytomegalovirus (HCMV), making it an attractive molecule for active and passive immunoprophylaxis. The region between aa 552 and 635 of HCMV gB (termed AD-1) has been identified as the immunodominant target for the humoral immune response following natural infection. AD-1 represents a complex domain which requires a minimal continuous sequence of more than 70 aa for antibody binding. Neutralizing as well as non-neutralizing antibodies can bind to AD-1 in a competitive fashion.
- Human Anti-AD1 Recombinant Antibody (HPAB-AP566-YC) (HPAB-AP566-YC)
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- Species Reactivity: HCMV
- Type: Human IgG1, λ
- Application: Funcs, ELISA, Neut
- Human Anti-AD1 Recombinant Antibody; Fab Fragment (HPAB-AP566-YC--F(E)) (HPAB-AP566-YC--F(E))
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- Species Reactivity: HCMV
- Type: Human Fab
- Application: ELISA, Neut, FuncS
- Human Anti-AD1 Recombinant Antibody; scFv Fragment (HPAB-AP566-YC-S(P)) (HPAB-AP566-YC-S(P))
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- Species Reactivity: HCMV
- Type: Human scFv
- Application: ELISA, Neut, FuncS
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For Research Use Only. Not For Clinical Use.