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αvβ6

The integrin αvβ6 is unique in that it is expressed exclusively in epithelial cells, and β6 partners only with αv forming a single heterodimer. During embryogenesis αvβ6 is expressed at high levels in the developing lung, skin and kidney epithelia and its expression is downregulated in healthy adult epithelia. However recent unpublished data from our laboratory suggest that αvβ6 is expressed at high levels in the adult hair follicles

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