Intracellular
Cell type enhanced (Langerhans cells, B-cells, Macrophages)
Low immune cell specificity
Cell line enhanced (Daudi, Karpas-707, U-698)
Component of the BCR(KBTBD8) E3 ubiquitin ligase complex, at least composed of CUL3, KBTBD8 and RBX1 (PubMed:26399832).
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For Research Use Only. Not For Clinical Use.