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KDM5D

Histone demethylase that specifically demethylates Lys-4 of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 Lys-9, H3 Lys-27, H3 Lys-36, H3 Lys-79 or H4 Lys-20. Demethylates trimethylated and dimethylated but not monomethylated H3 Lys-4. May play a role in spermatogenesis.
Protein class

Enzymes, Plasma proteins, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Plasma cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HEL, U-698)

Interaction

Interacts with PCGF6, MSH5, ZMYND8, AR.

Molecular function

Chromatin regulator, Dioxygenase, Oxidoreductase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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