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PUM3
Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity).
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HDLM-2, HEL)
Interaction
Interacts with PARP1 (via catalytic domain).
Molecular function
DNA-binding, RNA-binding
More Types Infomation
- A*02:01/Human PUM3 (RTLDKVLEV) MHC Tetramer (MHC-CN1180)
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- Class: Class I
- Antigen: PUM3
- Antigen Species: Human
- Peptide: RTLDKVLEV
- Conjugate: Unconjugated
- FITC-A*02:01/Human PUM3 (RTLDKVLEV) MHC Tetramer (MHC-CN1179)
-
- Class: Class I
- Antigen: PUM3
- Antigen Species: Human
- Peptide: RTLDKVLEV
- Conjugate: FITC
- APC-A*02:01/Human PUM3 (RTLDKVLEV) MHC Tetramer (MHC-CN1178)
-
- Class: Class I
- Antigen: PUM3
- Antigen Species: Human
- Peptide: RTLDKVLEV
- Conjugate: APC
- PE-A*02:01/Human PUM3 (RTLDKVLEV) MHC Tetramer (MHC-CN1177)
-
- Class: Class I
- Antigen: PUM3
- Antigen Species: Human
- Peptide: RTLDKVLEV
- Conjugate: PE
- APC-A*02:01/Human HA-8 (RTLDKVLEV) MHC Tetramer (MHC-LC685)
-
- Class: Class I
- Antigen: HA-8
- Antigen Species: Human
- Peptide: RTLDKVLEV
- Conjugate: APC
- PE-A*02:01/Human HA-8 (RTLDKVLEV) MHC Tetramer (MHC-LC684)
-
- Class: Class I
- Antigen: HA-8
- Antigen Species: Human
- Peptide: RTLDKVLEV
- Conjugate: PE
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For Research Use Only. Not For Clinical Use.