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SLC44A4 (AGS-5)
The protein encoded by this gene may be a sodium-dependent transmembrane transport protein involved in the uptake of choline by cholinergic neurons. Defects in this gene can cause sialidosis, a lysosomal storage disease. Three transcript variants encoding different isoforms have been found for this gene.
- Anti-CTL4-mc-MMAE ADC (ADC-179LCT)
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- Target: CTL4
- Linker: Mc (maleimidocaproyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CTL4-vc-mc-MMAE ADC (ADC-178LCT)
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- Target: CTL4
- Linker: VC-Mc- (valine-citrulline-maleimidocaproyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-SLC44A4 (AGS-5)-vc-MMAE ADC (ADC-177LCT)
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- Target: SLC44A4 (AGS-5)
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-SLC44A4 (AGS-5)-vc-MMAE ADC (ADC-019LZY)
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- Target: SLC44A4 (AGS-5)
- Linker: VC (valine-citrulline)
- Drug: MMAE (monomethyl auristatin E)
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For Research Use Only. Not For Clinical Use.