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TCIRG1
The anti-TIRC7 antibody can be used for the treatment of an inflammatory disease, particularly rheumatoid arthritis.
Protein class
Disease related genes, Human disease related genes, Metabolic proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Gastric mucus-secreting cells, Macrophages, Kupffer cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HMC-1, RPMI-8226)
Interaction
V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits ATP6AP1/Ac45 and ATP6AP2/PRR (By similarity).
More Types Infomation
- Recombinant Anti-Human TCIRG1 Antibody scFv Fragment (MOB-3563z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: IP, IF, Biosensors, FuncS
- Recombinant Anti-Human TCIRG1 Antibody Fab Fragment (MOB-3563z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, Neut, FuncS
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- Species Reactivity: human
- Type: Mouse IgG2a, κ
- Application: WB, IP, ELISA
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab) (HPAB-0341-WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA
- Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab) (HPAB-0340-WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA
- Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab); Fab Fragment (HPAB-0341-WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
-
- Derivation: Chimeric (human/mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Human Anti-TCIRG1 Antibody, mRNA (TAB-594CL-mRNA)
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- Species Reactivity: Human
- Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab); scFv Fragment (HPAB-0341-WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab); scFv Fragment (HPAB-0340-WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Anti-Human TCIRG1 Recombinant Antibody (TAB-594CL)
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- Derivation: Chimeric (human/mouse)
- Species Reactivity: Human
- Type: Antibody
- Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab); Fab Fragment (HPAB-0340-WJ-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.