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TFAP2C
The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Suprabasal keratinocytes, Basal keratinocytes, Basal squamous epithelial cells, Syncytiotrophoblasts, Cytotrophoblasts, Squamous epithelial cells, Breast myoepithelial cells, Breast glandular cells, Extravillous trophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (BEWO, MCF7, SK-BR-3, T-47d, WM-115)
Interaction
Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity). Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I. Interacts with KCTD1; this interaction represses transcription activation. Interacts with CITED2 (via C-terminus); the interaction stimulates TFAP2B-transcriptional activity. Interacts with MTA1.
Molecular function
Activator, DNA-binding
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC, ICC, IHC-P, WB
- Recombinant Mouse Anti-TFAP2C Antibody (VS-0923-FY150) (VS-0923-FY150)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, IP
-
- Type: Mouse IgG1
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For Research Use Only. Not For Clinical Use.