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TUBB1
Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Human ortholog(s) of this gene implicated in autosomal dominant macrothrombocytopenia TUBB1-related. Orthologous to human TUBB1 (tubulin beta 1 class VI).
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Macrophages)
Immune cell specificity
Group enriched (basophil, neutrophil)
Cell line specificity
Cell line enriched (HEL)
Interaction
Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells. Interacts with RANBP10.
More Types Infomation
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- Class: Class I
- Antigen: Tubulin
- Antigen Species: Gallus gallus
- Peptide: REVDEQLLSV
- Conjugate: PE
-
- Class: Class I
- Antigen: Tubulin
- Antigen Species: Gallus gallus
- Peptide: REVDEQLLSV
- Conjugate: APC
-
- Class: Class I
- Antigen: Tubulin
- Antigen Species: Gallus gallus
- Peptide: REVDEQLLSV
- Conjugate: BV421
- Mouse Anti-tubb1 Recombinant Antibody (VS3-WK1407) (VS3-WK1407)
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- Derivation: Mouse
- Species Reactivity: Zebrafish
- Type: Mouse IgG1
- Application: WB
-
- Derivation: Mouse
- Species Reactivity: Human, Mouse, Monkey, Rat
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
-
- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
- Mouse Anti-TUBB1 Recombinant Antibody (VS3-WK1157) (VS3-WK1157)
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- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB, ICC, IHC
- Mouse Anti-TUBB1 Recombinant Antibody (VS3-WK1156) (VS3-WK1156)
-
- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC
-
- Species Reactivity: Human, Mouse, Rat, Bovine, Rabbit
- Type: Mouse IgG
- Application: WB
-
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG
- Application: WB, IHC-P, IF
-
- Species Reactivity: Zebrafish
- Type: Mouse IgG
- Application: WB
-
- Species Reactivity: Human, Mouse, Monkey, Goat, Hamster, Rat, chlamydomonas
- Type: Mouse IgG
- Application: WB, ICC
-
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.