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ZWINT

Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Late spermatids, Erythroid cells, Spermatocytes, Extravillous trophoblasts, Spermatogonia)

Immune cell specificity

Immune cell enhanced (T-reg)

Cell line specificity

Low cell line specificity

Interaction

Interacts with ZW10 and MIS12. Interacts with the NDC80 subunit of the NDC80 complex specifically during mitosis. Also interacts with KNL1, CETN3, DSN1 and PMF1.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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