Loading...
CADM1
The monoclonal antibodies specifically bind to CADM1 with high affinity are used for treating various cancers, including lung cancer and pancreatic cancer, are disclosed.
Protein class
Human disease related genes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Astrocytes, Rod photoreceptor cells, Oligodendrocyte precursor cells, Oligodendrocytes, Bipolar cells, Muller glia cells, Alveolar cells type 1)
Immune cell specificity
Immune cell enhanced (myeloid DC, gdT-cell)
Cell line specificity
Cell line enhanced (CACO-2, WM-115)
Interaction
Homodimer (via Ig-like V-type domain) (PubMed:12050160, PubMed:23871486). Interacts with FARP1 (By similarity). Interacts (via Ig-like V-type domain) with CRTAM (via Ig-like V-type domain); the interaction competes with CRTAM homodimerization and CADM1 homodimerization (PubMed:15811952, PubMed:15781451, PubMed:23871486). Interacts (via C-terminus) with EPB41L3/DAL1 (PubMed:12234973, PubMed:21131357). The interaction with EPB41L3/DAL1 may act to anchor CADM1 to the actin cytoskeleton (PubMed:12234973). Interacts (via C-terminus) with MPP2 (via PDZ domain) (By similarity). Interacts (via C-terminus) with MPP3 (via PDZ domain) (PubMed:13679854). Interacts (via C-terminus) with PALS2 (via PDZ domain) (By similarity). (Microbial infection) Interacts with herpes virus 8 proteins vFLIP and vGPCR; these interactions are essential for NF-kappa-B activation.
Molecular function
Developmental protein
More Types Infomation
- Recombinant Anti-Human CADM1 Antibody (MOB-3779z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IP, FuncS
- Recombinant Anti-Human CADM1 Antibody scFv Fragment (MOB-3779z-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: IP, IF, Biosensors, FuncS
- Recombinant Anti-Human CADM1 Antibody Fab Fragment (MOB-3779z-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, FuncS
- Anti-Human CADM1 Recombinant Antibody (AB1) (TAB-1439CL)
-
- Type: Fully human antibody
- Application: ELISA
-
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Human CADM1 Recombinant Antibody (TAB-089CL)
-
- Species Reactivity: Human
- Type: Antibody
- Anti-Human CADM1 Recombinant Antibody Fab Fragment (AB3) (TAB-1441CL-F(E))
-
- Type: Fully human antibody
- Application: IF, FC, WB, ELISA
- Anti-Human CADM1 Recombinant Antibody scFv Fragment (AB6) (TAB-1444CL-S(P))
-
- Type: Fully human antibody
- Application: ELISA
- Anti-Human CADM1 Recombinant Antibody (AB6) (TAB-1444CL)
-
- Type: Fully human antibody
- Application: ELISA
- Anti-Human CADM1 Recombinant Antibody Fab Fragment (AB2) (TAB-1440CL-F(E))
-
- Type: Fully human antibody
- Application: IF, FC, WB, ELISA
- Anti-Human CADM1 Recombinant Antibody scFv Fragment (AB5) (TAB-1443CL-S(P))
-
- Type: Fully human antibody
- Application: ELISA
- Anti-Human CADM1 Recombinant Antibody (AB5) (TAB-1443CL)
-
- Type: Fully human antibody
- Application: ELISA
- Anti-Human CADM1 Recombinant Antibody Fab Fragment (AB1) (TAB-1439CL-F(E))
-
- Type: Fully human antibody
- Application: ELISA
- Human Anti-CADM1 Recombinant Antibody; Fab Fragment (TAB-1453CL-F(E)) (TAB-1453CL-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: FC, ADCC, FuncS
- Anti-Human CADM1 Recombinant Antibody scFv Fragment (AB4) (TAB-1442CL-S(P))
-
- Type: Fully human antibody
- Application: ELISA
- Anti-Human CADM1 Recombinant Antibody (AB4) (TAB-1442CL)
-
- Type: Fully human antibody
- Application: ELISA
- Anti-Human CADM1 Recombinant Antibody scFv Fragment (AB2) (TAB-1440CL-S(P))
-
- Type: Fully human antibody
- Application: IF, FC, WB, ELISA
- Anti-Human CADM1 Recombinant Antibody (AB3) (TAB-1441CL)
-
- Type: Fully human antibody
- Application: FC
- Anti-Human CADM1 Recombinant Antibody scFv Fragment (AB3) (TAB-1441CL-S(P))
-
- Type: Fully human antibody
- Application: IF, FC, WB, ELISA
- Anti-Human CADM1 Recombinant Antibody scFv Fragment (AB1) (TAB-1439CL-S(P))
-
- Type: Fully human antibody
- Application: IF, FC, WB, ELISA
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.