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CBX7

This gene encodes a protein that contains the CHROMO (CHRomatin Organization MOdifier) domain. The encoded protein is a component of the Polycomb repressive complex 1 (PRC1), and is thought to control the lifespan of several normal human cells.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Cardiomyocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HDLM-2, U-266/70)

Interaction

Component of a PRC1-like complex. Interacts with RING1 and RNF2/RING1B, but not with BMI1, EED or EZH2. Interacts with PCGF1, PCGF2, PCGF3, PCGF5 and PCGF6.

Molecular function

Chromatin regulator, Repressor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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