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CCL5

CCL5 (C-C Motif Chemokine Ligand 5) is a Protein Coding gene. Diseases associated with CCL5 include Ulcer Of Lower Limbs and Periapical Granuloma. Among its related pathways are PEDF Induced Signaling and Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chemokine activity. An important paralog of this gene is CCL3L3.
Protein class

Cancer-related genes, Human disease related genes, Plasma proteins

Predicted location

Membrane, Secreted (different isoforms)

Single cell type specificity

Group enriched (NK-cells, dendritic cells, T-cells)

Immune cell specificity

Immune cell enhanced (memory CD8 T-cell, gdT-cell)

Cell line specificity

Cell line enhanced (HL-60, NB-4, THP-1, U-937)

Interaction

Homo and heterooligomers with other chemokines. Interacts with the brown dog tick evasin-4.

Molecular function

Cytokine

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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