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CELF2

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons, Astrocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HEL, HMC-1, REH)

Interaction

Interacts with A1CF.

Molecular function

Repressor, RNA-binding

More Types Infomation

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