Disease related genes, Human disease related genes
Intracellular
Cell type enhanced (Early spermatids, Spermatocytes)
Not detected in immune cells
Cell line enhanced (HEL)
Forms homodimers (PubMed:27219064). Associates with microtubules plus ends; binds to beta-tubulin subunits exposed on microtubule outer surface at its distal tip; also associates with microtubule lattice (PubMed:19131341, PubMed:27219064, PubMed:27306797). Associated with the gamma-tubulin complex. Interacts with the head domain of EPB41 (PubMed:11003675). Interacts with LYST (PubMed:11984006). Interacts with CEP152 (via C-terminus) (PubMed:20852615). Interacts with STIL (PubMed:22020124, PubMed:25385835). Forms a complex with STIL and SASS6 (PubMed:22020124).
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For Research Use Only. Not For Clinical Use.