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CERS2

This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.
Protein class

Enzymes, Metabolic proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Hepatocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with ATP6V0C, ASGR1, ASGR2 and SLC22A1/OCT1 (PubMed:11543633). Interacts with ELOV1, HSD17B12 and TECR (PubMed:20937905). Interacts with NDUFS2 (By similarity).

Molecular function

Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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