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CLCN2

This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
Protein class

Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Distal enterocytes, Theca cells, Proximal enterocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Low cell line specificity

Molecular function

Chloride channel, Ion channel, Voltage-gated channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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