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CTNNA2

CTNNA2 (Catenin (Cadherin-Associated Protein), Alpha 2) is a Protein Coding gene. Diseases associated with CTNNA2 include mixed germ cell cancer. Among its related pathways are Developmental Biology and Pathways in cancer. GO annotations related to this gene include structural molecule activity and structural constituent of cytoskeleton. An important paralog of this gene is CTNNA3.
Protein class

Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Astrocytes, Excitatory neurons, Oligodendrocyte precursor cells, Inhibitory neurons, Early spermatids)

Immune cell specificity

Immune cell enriched (basophil)

Cell line specificity

Cell line enhanced (AF22, Karpas-707, NTERA-2, SCLC-21H, SH-SY5Y)

Interaction

Interacts with CDH1 and CDH2 (By similarity). Interacts with ZNF639; recruits CTNNA2 to the nucleus (PubMed:16182284). Interacts with F-actin (PubMed:30013181).

Molecular function

Developmental protein

More Types Infomation

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