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CYP3A5

CYP3A5 (Cytochrome P450 Family 3 Subfamily A Member 5) is a Protein Coding gene. Diseases associated with CYP3A5 include Hypertension, Essential and Tacrolimus Dose Selection. Among its related pathways are Tamoxifen Pathway, Pharmacokinetics and Vinka Alkaloid Pathway, Pharmacokinetics. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and heme binding. An important paralog of this gene is CYP3A4.
Protein class

Cancer-related genes, Enzymes, Metabolic proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Gastric mucus-secreting cells, Hepatocytes, Paneth cells, Distal enterocytes, Urothelial cells, Cholangiocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CACO-2, Hep G2, OE19)

Molecular function

Monooxygenase, Oxidoreductase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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