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DGAT1

This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases.
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Proximal enterocytes, Distal enterocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (Hep G2, PC-3)

Interaction

Homodimer or homotetramer; both forms have similar enzymatic activities.

Molecular function

Acyltransferase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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