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DLX6

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. This family is comprised of at least 6 different members that encode proteins with roles in forebrain and craniofacial development. This gene is in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Extravillous trophoblasts, Endometrial ciliated cells, Cytotrophoblasts, Glandular and luminal cells, Early spermatids, Syncytiotrophoblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AN3-CA, BEWO, HAP1, SH-SY5Y, SuSa)

Molecular function

Developmental protein, DNA-binding

More Types Infomation

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