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DNALI1
This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008]
Predicted location
Intracellular
Single cell type specificity
Group enriched (Late spermatids, Early spermatids, Respiratory ciliated cells, Endometrial ciliated cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, ASC TERT1, hTERT-RPE1, RPTEC TERT1, SH-SY5Y, T-47d)
Interaction
Interacts with CFAP45 (PubMed:33139725). Interacts with DYNC1H1 (By similarity).
Molecular function
Motor protein
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.