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DOT1L

The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Cone photoreceptor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Low cell line specificity

Interaction

Interacts with MLLT10.

Molecular function

Chromatin regulator, DNA-binding, Methyltransferase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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