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ERCC6L
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Erythroid cells, Granulosa cells, Squamous epithelial cells, Spermatogonia, Spermatocytes)
Immune cell specificity
Immune cell enriched (NK-cell)
Cell line specificity
Low cell line specificity
Interaction
Interacts with PLK1, which phosphorylates it (PubMed:17218258, PubMed:17671160, PubMed:28977671). Both proteins are mutually dependent on each other for correct subcellular localization (PubMed:17218258, PubMed:17671160). Interacts (via N-terminal TPR repeat) with BEND3 (via BEN domains 1 and 3); the interaction is direct (PubMed:28977671).
Molecular function
DNA-binding, Helicase, Hydrolase
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.