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FBLN2
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures.
Protein class
Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Fibroblasts, Peritubular cells, Leydig cells, Adipocytes, Endometrial stromal cells)
Immune cell specificity
Immune cell enhanced (myeloid DC, naive CD8 T-cell)
Cell line specificity
Cell line enhanced (ASC diff, fHDF/TERT166, HMC-1, HSkMC, U-2197)
Interaction
Homotrimer; disulfide-linked. Interacts with LAMA2 (By similarity). Interacts with FBN1 (via N-terminal domain). Forms a ternary complex with ELN and FBN1 (PubMed:17255108).
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.